The thermal cure behavior of diglycidyl ether bisphenol-A/carboxylated polyester hybrid powder coating system in the absence and presence of catalyst was monitored using differential scanning calorimetry. Curing temperatures were between 160 and 200 °C. The experimental results showed an autocatalytic behavior of the reaction, which could be described by the model proposed by Kamal. This model includes two rate constants k1 and k2 and two reaction orders m and n.